Tumor sequencing dataset from 17 individuals with biallelic germline pathogenic variants in CHEK2
type: Distribution
description: WES data of 17 tumors from 9 individuals that have biallelic germline CHEK2 pathogenic variants. Shallow whole genome sequencing files from 16 tumors samples from 9 individuals with germline biallleic pathogenic variants in CHEK2.
issued: 2026-04-12T11:34:23.738085
language: ENG
license: niet-open
modified: 2026-04-12T11:34:23.716692
rights: EGAD00001004534
rights: RightsStatement
access URL: https://ega-archive.org/datasets/EGAD50000000112
byte size: 383600000000
media type: htts://publications.europa.eu/resource/authority/file-type/BIN

COVID-19 dataset with individual level data
type: Dataset
creator: Agent
  identifier: CSC - IT Center for Science (Finland)
  name: https://ror.org/04m8m1253
description: This dataset contains individual level data from 42193 individuals from COVID Population 12 Italy, Subgroup 2.
issued: 2024-11-08T04:00:00+00:00
language: en
modified: 2024-11-08T05:00:00+00:00
provenance: ProvenanceStatement
publisher: CSC - IT Center for Science (Finland)
contact point: Kind
  fn: Dylan Spalding
theme: HEAL

Tumor sequencing dataset from 17 individuals with biallelic germline pathogenic variants in CHEK2
type: Dataset
applicable legislation: oj
number of records: 33
number of unique individuals: 9
access rights: NON PUBLIC
creator: Radboudumc
description: "This study investigated the molecular landscape of 17 tumors from 9 individuals with biallelic germline pathogenic variants in CHEK2. Tumors included breast and non-breast cancers, and WES and sWGS bam files from the tumors are included in this submission. WES data was aligned to GRCh37 and sWGS data to GRCh38."
is referenced by: pkae044
issued: 2026-04-10T11:03:30.953647
language: ENG
modified: 2026-04-12T11:34:23.702721
provenance: ProvenanceStatement
publisher: Radboudumc
spatial: NLD
type: STATISTICAL
contact point: Kind
  fn: Radboudumc
  has URL: https://ega-archive.org/dacs/EGAC00001001102
keyword: WES
keyword: Genome
keyword: WGS
keyword: Germline CHEK2 deficiency
keyword: Tumor
qualified attribution: Attribution
  agent: Richarda de Voer
  had role: principalInvestigator
theme: HEAL
has legal basis: Consent
has personal data: DNACode
has purpose: NonCommercialResearch

PRIDE Study paternal questionnaire data
type: Dataset
creator: Marleen van Gelder
description: Questionnaire data focusing on paternal exposures the 3 months before conception. Completed by the biological father, <50% participation rate.
issued: 2024-12-30T23:00:00+00:00
language: en
modified: 2026-04-12T11:35:18.569435
provenance: ProvenanceStatement
publisher: Radboudumc
theme: HEAL

GoE Finnish Dataset
type: Dataset
applicable legislation: oj
health category: HealthCategoryHumanGenomic
number of records: 20343
access rights: PUBLIC
conforms to: ExternallyGoverned
creator: Agent
  name: https://ror.org/04m8m1253
description: GoE Finnish Dataset produced from legacy data
issued: 2026-04-10T11:05:49.652500
language: en
modified: 2026-04-12T11:35:46.120004
provenance: ProvenanceStatement
theme: HEAL

COVID-19 GWAS and Allele Frequency Lookup Dataset for GDI MS 8
type: Dataset
creator: National Bioinformatics Infrastructure Sweden
description: This is the first part of the split 11 of the synthetic data dedicated for the GDI MS8
issued: 2024-07-07T11:11:11+00:00
language: en
modified: 2024-06-04T13:36:10+00:00
provenance: ProvenanceStatement
publisher: National Bioinformatics Infrastructure Sweden
contact point: Kind
  fn: Data Access Committee of NBIS
  has UID: 00enajs79
keyword: COVID19
keyword: Smokers
theme: HEAL

Clinical Chemistry
type: Dataset
creator: Eline Slagboom
creator: Simon Mooijaart
creator: Joris Deelen
creator: Marian Beekman
creator: Diana van Heemst
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of the offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: 10.1038/sj.ejhg.5201508; Westendorp et al 2009, doi: 10.1111/j.1532-5415.2009.02381.x). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79) as population based controls. It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. The dataset of the LLS IOP1 Partner Offspring consists of the 1671 offspring of nonagenarian siblings and their 744 partners from 421 families of whom we have physical measurements, biosamples, biomarkers, and questionnaire data. We followed this group of 2,415 middle-aged participants for their vital status till 2020, for their morbidity status till 2017.
issued: 2024-11-07T13:35:33+00:00
language: en
modified: 2024-11-07T13:36:41+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

CMMRD tumors sequencing data
type: Distribution
description: Whole exome sequencing data from the tumors of individuals with constitutional mismatch repair deficiency. These are 16 tumors from the bigger study of 41 tumors in total (from 17 individuals in total).
format: format 3462
issued: 2026-04-12T11:35:04.041699
language: ENG
license: niet-open
modified: 2026-04-12T11:35:04.030522
rights: RightsStatement
rights: EGAD00001004534
access URL: https://ega-archive.org/datasets/EGAD50000000113
byte size: 44600000000

Test dataset Hannah
type: Dataset
applicable legislation: oj
retention period: PeriodOfTime
  end date: 2025-04-05
  start date: 2025-04-19
access rights: NON PUBLIC
creator: Albert Einstein
description: test dataset
issued: 2025-04-21T06:08:00+00:00
language: en
modified: 2025-04-15T02:09:00+00:00
provenance: ProvenanceStatement
publisher: Albert Einstein
temporal: PeriodOfTime
  end date: 2025-04-13T22:00:00+00:00
  start date: 2025-04-28T22:00:00+00:00
identifier: Identifier
  notation: nc217b86fa11f4716b59d81f0d523b1c8b6
version notes: This is the first version
contact point: Kind
  fn: Albert Einstein
keyword: more test
keyword: test data
keyword: hoi
qualified attribution: Attribution
  agent: Albert Einstein
  had role: funder
qualified relation: Relationship
  relation: dataset
  had role: example.com
theme: HEAL
has quality annotation: Annotation
  has body: dataset
  has target: example.com

test dataset aux classes
type: Dataset
applicable legislation: oj
access rights: PUBLIC
conforms to: Q19597236
creator: Albert Einstein
description: Test dataset for aux classes
issued: 2025-09-10T11:32:55.662911
language: en
modified: 2026-04-12T11:36:50.962047
provenance: ProvenanceStatement
publisher: Albert
contact point: Kind
  fn: Albert Einstein
keyword: test
keyword: tryout
keyword: aux classes
qualified attribution: Attribution
  agent: Funder1
  had role: funder
qualified relation: Relationship
  had role: last
theme: HEAL

Participant information
type: Dataset
creator: Simon Mooijaart
creator: Marian Beekman
creator: Eline Slagboom
creator: Diana van Heemst
creator: Joris Deelen
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of the offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: 10.1038/sj.ejhg.5201508; Westendorp et al 2009, doi: 10.1111/j.1532-5415.2009.02381.x). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. The dataset of the LLS IOP1 Nonagenarian Siblings consists of 944 long-lived siblings from 421 families of whom we have biosamples, biomarkers, and questionnaire data. We followed these nonagenarian participants for their vital status till 2020.
issued: 2022-04-28T15:40:58+00:00
language: en
modified: 2022-06-13T12:03:46+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

UroLife study fluid intake and micturition diary
type: Dataset
applicable legislation: oj
has code values: Q116728508
health category: Q116728508
max typical age: 80
min typical age: 18
number of records: 1146
number of unique individuals: 1146
population coverage: Patients with newly diagnosed non-muscle invasive bladder cancer aged 18-80 years from the Netherlands diagnosed between 2014-2021
retention period: PeriodOfTime
  end date: 2037-07-04
  start date: 2022-07-04
access rights: NON PUBLIC
accrual periodicity: NOT PLANNED
creator: Radboudumc
description: A 4-day fluid and micturition diary was completed at 3 (n=1146) and 15 months (n=1000) after diagnosis.
issued: 2024-12-30T23:00:00+00:00
language: ENG
modified: 2026-04-12T11:34:48.248268
provenance: ProvenanceStatement
publisher: Radboudumc
spatial: NLD
temporal: PeriodOfTime
  end date: 2022-07-04T22:00:00+00:00
  start date: 2014-03-31T22:00:00+00:00
keyword: fluid intake
keyword: micturition
qualified attribution: Attribution
  agent: Alina Vrieling
  had role: principalInvestigator
qualified attribution: Attribution
  agent: KWF Kankerbestrijding
  had role: funder
qualified attribution: Attribution
  agent: World Cancer Research Fund Netherlands
  had role: funder
theme: HEAL
has legal basis: InformedConsent
has purpose: AcademicResearch

Test Dataset
type: Dataset
access rights: PUBLIC
creator: Bar
description: Foo Bar
issued: 2025-09-10T11:33:02.803900
language: en
modified: 2026-04-12T11:36:20.389107
provenance: ProvenanceStatement
publisher: Foo Bar
contact point: Kind
  fn: Foo Bar
keyword: bar
keyword: foo
theme: example.com

ReLife study abdominal CT scans
type: Dataset
applicable legislation: oj
has code values: Q18556340
health category: Q1164529
max typical age: 75
min typical age: 18
number of records: 349
number of unique individuals: 349
population coverage: patients with localized stage I-III renal cell cancer aged 18-75 years from the Netherlands recruited from January 2018 to June 2021
retention period: PeriodOfTime
  end date: 2038-04-19
  start date: 2023-04-19
access rights: NON PUBLIC
accrual periodicity: NOT PLANNED
creator: Radboudumc
description: Abdominal CT scans are availabe for n=349 patients.
issued: 2024-12-30T23:00:00+00:00
language: ENG
modified: 2026-04-12T11:34:14.687711
provenance: ProvenanceStatement
publisher: Radboudumc
spatial: NLD
temporal: PeriodOfTime
  end date: 2023-04-19T22:00:00+00:00
  start date: 2018-02-05T23:00:00+00:00
keyword: abdominal CT scans
qualified attribution: Attribution
  agent: Alina Vrieling
  had role: principalInvestigator
qualified attribution: Attribution
  agent: World Cancer Research Fund Netherlands
  had role: funder
qualified attribution: Attribution
  agent: KWF Kankerbestrijding
  had role: funder
theme: HEAL
has legal basis: InformedConsent
has purpose: AcademicResearch

CKAN
type: Catalog
language: nl
modified: 2026-04-12T11:37:11.128299
dataset: SYNTHETIC Norwegian Colorectal Cancer genomic dataset generated in EOSC4Cancer

PRIDE Study pharmacy data
type: Dataset
creator: Marleen van Gelder
description: Details on prescription medication fills in the three months before the last menstrual period until 6 months after the estimated date of delivery. Necessitates additional consent, provided by ~75% of participants.
issued: 2024-12-30T23:00:00+00:00
language: en
modified: 2026-04-12T11:35:20.738408
provenance: ProvenanceStatement
publisher: Radboudumc
theme: HEAL

BioCAPTURE registry data
type: Dataset
creator: Juul van den Reek
creator: Elke de Jong
description: In this ongoing prospective cohort study containing data of 24 Dutch hospitals, patients with psoriasis are asked to be included for the BioCAPTURE registry at the moment of initiating a biologic. In case of inclusion, prospecitve data collection starts and is retrieved from electronic patient records (demographics, intoxications, comorbidities, medical history, psoriasis treatment history, disease activity scores (incl. Psoriasis Area and Severity Index (PASI)), side effects, dosages of biologics. Patients are also asked for questionnaire research participation. Those that consent are sent web-based questionnaires every three months in the first year after starting a specific biologic, and annualy in the years thereafter. In case they switch to another biologic, this series starts again. Questionnaires focus on a broad range of topics, including dermatology-related quality of life, treatement satistfaction with medication, health status, work productivity, healthcare usage. The current analytical dataset includes >2700 treatement episodes of 1550 unique patients.
issued: 2024-12-09T23:00:00+00:00
language: en
modified: 2026-04-12T11:33:47.714277
provenance: ProvenanceStatement
publisher: Radboudumc
theme: HEAL

ReLife study blood samples
type: Dataset
applicable legislation: oj
has code values: Q18556337
health category: Q1164529
max typical age: 75
min typical age: 18
number of records: 335
number of unique individuals: 335
population coverage: patients with localized stage I-III renal cell cancer aged 18-75 years from the Netherlands recruited from January 2018 to June 2021
retention period: PeriodOfTime
  end date: 2038-04-19
  start date: 2023-04-19
access rights: NON PUBLIC
accrual periodicity: NOT PLANNED
creator: Radboudumc
description: Serum and EDTA plasma samples were collected at 3 (n=335), 12 (n=266) and 24 months (n=237) after surgery. EDTA plasma samples have been analysed for CRP, IL-6, adiponectin, and leptin.
issued: 2024-12-30T23:00:00+00:00
language: ENG
modified: 2026-04-12T11:33:45.890373
provenance: ProvenanceStatement
publisher: Radboudumc
spatial: NLD
temporal: PeriodOfTime
  end date: 2023-04-19T22:00:00+00:00
  start date: 2018-02-05T23:00:00+00:00
keyword: EDTA plasma
keyword: serum
keyword: blood
qualified attribution: Attribution
  agent: KWF Kankerbestrijding
  had role: funder
qualified attribution: Attribution
  agent: Alina Vrieling
  had role: principalInvestigator
qualified attribution: Attribution
  agent: World Cancer Research Fund Netherlands
  had role: funder
theme: HEAL
has legal basis: InformedConsent
has purpose: AcademicResearch

SYNTHETIC Norwegian Colorectal Cancer genomic dataset generated in EOSC4Cancer
type: Dataset
creator: Agent
description: SYNTHETIC This dataset contains 10 tumor and normal pairs synthetic WGS data of colorectal cancer that were simulated in a standard format of Illumina paired-end reads. NEAT read simulator (version 3.0, https://github.com/zstephens/neat-genreads) is utilized to synthetize these 10 pairs tumor and normal WGS data. In the procedure of data generation, simulated parameters (i.e., sequencing error statistics, read fragment length distribution and GC% coverage bias) are learned from data models provided by NEAT. The average sequencing depth for tumor and normal samples aims to reach around 110X and 60X, respectively. For generation of synthetic normal WGS data per each sample, a germline variant profile from a real patient is down-sampled randomly, which includes 50% germline variants of such a patient. It is then mixed together with an in silico germline variant profile that is modelled randomly using an average mutation rate (0.001), finally constituting a full germline profile for normal synthetic WGS data. For generation of synthetic tumor WGS data per each sample, a pre-defined somatic short variant profile (SNVs+Indels) learn from a real CRC patient is added to the germline variant profile used for creating normal synthetic WGS data of the same patient, which is utilized to produce simulated sequences. Neither copy number profile nor structural variation profile is introduced into the tumor synthetic WGS data. Tumor content and ploidy are assumed to be 100% and 2.
issued: 2024-04-30T00:00:00+00:00
modified: 2026-04-12T11:33:27.341232
provenance: ProvenanceStatement
publisher: University of Oslo
contact point: Kind
  fn: Sen Zhao
  has UID: Sen-Zhao-7
keyword: synthetic
keyword: colorectal_tumor
keyword: ngs
keyword: wgs
keyword: normal_tumor_pair
theme: Colorectal cancer

FU Castor Balanstesten
type: Dataset
creator: Joris Deelen
creator: Diana van Heemst
creator: Eline Slagboom
creator: Simon Mooijaart
creator: Marian Beekman
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of this offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: [10.1038/sj.ejhg.5201508](http://https://www.nature.com/articles/5201508); Westendorp et al 2009, doi: [10.1111/j.1532-5415.2009.02381.x](http://https://agsjournals.onlinelibrary.wiley.com/doi/10.1111/j.1532-5415.2009.02381.x)). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. Of all LLS participants HRC1.1 imputed genotypes are available.
issued: 2024-11-12T14:31:19+00:00
language: en
modified: 2024-11-12T14:31:43+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

Test Distribution
type: Distribution
format: text
issued: 2026-04-12T11:37:06.781044
language: en
license: cc-by-0
modified: 2026-04-12T11:37:06.774296
rights: rights
rights: RightsStatement
status: DEVELOP
access URL: http://example.com/access/url
byte size: 1024

CSCFI
type: Agent

Front-end test
type: Dataset
applicable legislation: oj
access rights: PUBLIC
creator: blaa
description: blaa
issued: 2026-04-11T11:19:44.573718
language: en
modified: 1998-12-31T23:00:00+00:00
provenance: ProvenanceStatement
publisher: blaa
contact point: Kind
  fn: Hello
keyword: blaa
theme: HEAL

SignalingLipids Overview
type: Dataset
creator: Eline Slagboom
creator: Simon Mooijaart
creator: Diana van Heemst
creator: Joris Deelen
creator: Marian Beekman
description: From the group of 343 couples (Ntotal=686_ LLS PartnerOffspring that participated in the LLS between 2006 and 2008, 500 participants were examined for the third time between 2009 and 2010. In total 250 offspring-partners couples participated, with a mean age of 66 years. Fasted blood was drawn and serum/plasma and viable PBMCs were isolated and stored. All participant were subjected to cognitive tests (ACS-90, STROOP, Picture Word Learning test, LOT, Apathy scale, CES-D), and in 367 participants 3Tesla brain MRI scans were performed and of 341 participants CT-scan of abdomen was performed.
issued: 2024-11-07T14:12:43+00:00
language: en
modified: 2024-11-07T14:13:14+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

PRIDE-BIOME project
type: Dataset
creator: Marleen van Gelder
description: Subproject among 116 PRIDE Study participants. Gut microbiome data for maternal samples collected at gestational weeks 20 and 34, and 2 months after the estimated date of delivery; infant samples at 2, 4, 6, 9, and 12 months of age.
issued: 2024-12-30T23:00:00+00:00
language: en
modified: 2026-04-12T11:35:11.358034
provenance: ProvenanceStatement
publisher: Radboudumc
theme: HEAL

Visit measures
type: Dataset
creator: Joris Deelen
creator: Diana van Heemst
creator: Marian Beekman
creator: Simon Mooijaart
creator: Eline Slagboom
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of the offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: 10.1038/sj.ejhg.5201508; Westendorp et al 2009, doi: 10.1111/j.1532-5415.2009.02381.x). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. The dataset of the LLS IOP1 Nonagenarian Siblings consists of 944 long-lived siblings from 421 families of whom we have biosamples, biomarkers, and questionnaire data. We followed these nonagenarian participants for their vital status till 2020.
issued: 2022-04-29T08:15:08+00:00
language: en
modified: 2022-06-13T12:03:59+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

TRACK-PD
type: Dataset
applicable legislation: oj
access rights: NON PUBLIC
creator: Maastricht UMC+
description: Data van het TRACK-PD cohort, inclusief klinische data, 7T MRI, biomaterialen en wearable data.
issued: 2026-04-10T11:03:43.086686
language: en
modified: 2026-04-12T11:34:25.654295
provenance: ProvenanceStatement
publisher: Maastricht UMC+
contact point: Kind
  fn: TRACK-PD Cohort
keyword: Parkinson
keyword: TRACK-PD
keyword: NPC
qualified attribution: Attribution
  agent: Mark Kuijf
  had role: principalInvestigator
theme: HEAL
has purpose: ResearchAndDevelopment

POM clinical data
type: Dataset
creator: Bas Bloem
description: Clinical data of the Personalized Parkinson Project, including motor scores, cognitive and neuropsychiatric assessments, autonomic symptoms, sleep and quality of life.
issued: 2025-04-03T22:00:00+00:00
language: en
modified: 2026-04-12T11:35:33.034383
provenance: ProvenanceStatement
publisher: Radboudumc
theme: HEAL

LLS_IOP3_OLINKcardiomatebolic_measures
type: Dataset
creator: Simon Mooijaart
creator: Joris Deelen
creator: Eline Slagboom
creator: Diana van Heemst
creator: Marian Beekman
description: From the group of 343 couples (Ntotal=686_ LLS PartnerOffspring that participated in the LLS between 2006 and 2008, 500 participants were examined for the third time between 2009 and 2010. In total 250 offspring-partners couples participated, with a mean age of 66 years. Fasted blood was drawn and serum/plasma and viable PBMCs were isolated and stored. All participant were subjected to cognitive tests (ACS-90, STROOP, Picture Word Learning test, LOT, Apathy scale, CES-D), and in 367 participants 3Tesla brain MRI scans were performed and of 341 participants CT-scan of abdomen was performed.
issued: 2024-02-09T08:26:50+00:00
language: en
modified: 2024-02-09T08:27:25+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

excel
type: Distribution
format: excel
issued: 2026-04-12T11:37:11.147303
language: en
license: RESTRICTED
modified: 2026-04-12T11:37:11.136498
rights: RightsStatement
rights: cc
status: COMPLETED
access URL: http://www.example.com/info
byte size: 12345

EATRIS-Plus multi-omics data of a human reference cohort
type: Dataset
applicable legislation: oj
max typical age: 61
min typical age: 23
number of unique individuals: 125
population coverage: A representative subset (age and sex balanced) of 125 samples was selected, sex balanced, with an age span ranging from 23 to 61 years.
access rights: PUBLIC
creator: Radboudumc
creator: European Infrastructure for Translational Medicine
description: In this reference study, blood samples of 125 healthy individuals were analyzed with a wide range of -omics technologies, resulting in the most comprehensive -omics profiling data set that is publicly available. The molecular measurements that are available here, can be used as reference values for any future (multi-)omics studyies. Along with phenotypic information (Sex, Age, BMI etc. and measured cell types levels) on the healthy subjects.
issued: 2024-03-11T23:00:00+00:00
language: ENG
modified: 2026-04-12T11:34:51.860970
provenance: ProvenanceStatement
publisher: Radboudumc
spatial: CZE
contact point: peter-bram.thoen@radboudumc.nl
keyword: Personalized medicine
keyword: Healthy population
keyword: Metabolomics
keyword: Epigenomics
keyword: Transcriptomics
keyword: Multi-omics
keyword: Proteomics
keyword: Genomics
keyword: Lipidomics
qualified attribution: Attribution
  agent: Nederlandse Organisatie voor Wetenschappelijk Onderzoek
  had role: funder
qualified attribution: Attribution
  agent: ELIXIR-CZ
  had role: funder
qualified attribution: Attribution
  agent: Horizon 2020
  had role: funder
theme: HEAL

Q1 FFQ Macronutrients
type: Dataset
creator: Simon Mooijaart
creator: Marian Beekman
creator: Diana van Heemst
creator: Eline Slagboom
creator: Joris Deelen
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of this offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: [10.1038/sj.ejhg.5201508](http://https://www.nature.com/articles/5201508); Westendorp et al 2009, doi: [10.1111/j.1532-5415.2009.02381.x](http://https://agsjournals.onlinelibrary.wiley.com/doi/10.1111/j.1532-5415.2009.02381.x)). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. Of all LLS participants HRC1.1 imputed genotypes are available.
issued: 2024-11-12T14:55:12+00:00
language: en
modified: 2024-11-12T14:55:53+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

POM biomaterials
type: Dataset
creator: Bas Bloem
description: Biomaterials of the Personalized Parkinson Project, including blood, CSF and stool samples.
issued: 2025-04-03T22:00:00+00:00
language: en
modified: 2026-04-12T11:33:43.060378
provenance: ProvenanceStatement
publisher: Radboudumc
theme: HEAL

Test dataset 2
type: Dataset
applicable legislation: oj
min typical age: 18
number of unique individuals: 1234
retention period: PeriodOfTime
  end date: 2025-04-05
  start date: 2025-04-21
access rights: NON PUBLIC
creator: Albert Einstein
description: Test dataset nr 2
issued: 2025-09-10T11:34:34.997286
language: en
modified: 2025-04-16T02:08:00+00:00
provenance: ProvenanceStatement
publisher: Albert Einstein
  type: Agent
  identifier: Albert Einstein
temporal: PeriodOfTime
  end date: 2025-04-13T22:05:00+00:00
  start date: 2025-03-31T22:00:00+00:00
identifier: Identifier
  notation: ne615e7065b7b424993741045dcd4f365b5
version notes: First version of this awesome dataset
contact point: Kind
  fn: Albert
keyword: test test
keyword: test dataset
qualified attribution: Attribution
  agent: Albert
  had role: processor
qualified relation: Relationship
  had role: related
theme: HEAL
has quality annotation: Annotation
  has body: link-relations.xhtml
has legal basis: Consent
has personal data: Gender
has purpose: ImproveHealthcare

Nightingale
type: Dataset
creator: Diana van Heemst
creator: Joris Deelen
creator: Marian Beekman
creator: Simon Mooijaart
creator: Eline Slagboom
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of the offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: 10.1038/sj.ejhg.5201508; Westendorp et al 2009, doi: 10.1111/j.1532-5415.2009.02381.x). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. The dataset of the LLS IOP1 Nonagenarian Siblings consists of 944 long-lived siblings from 421 families of whom we have biosamples, biomarkers, and questionnaire data. We followed these nonagenarian participants for their vital status till 2020.
issued: 2022-04-29T08:17:24+00:00
language: en
modified: 2022-06-13T12:01:38+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

COMODULATE Lab results LUMC
type: Dataset
applicable legislation: oj
access rights: RESTRICTED
creator: Simon P. Jochems
creator: Jutte J.C. de Vries, Principal Investigator
description: COMODULATE Lab results LUMC Research laboratory data of the LUMC COMODULATE cohort. Retrospective observational non-WMO study including COVID-19 and Influenza patients with and without ARDS from 2019 to 2024. Host transcriptomics and inflammatory proteomics variables were measured in respiratory samples. Principle Investigator, Jutte JC de Vries, LUCID
is referenced by: personalised-targeted-immunomodulation-patients-ards-related-covid19-and-future-pandemic
issued: 2025-09-10T11:34:22.455580
language: en
modified: 2026-04-12T11:36:12.055315
provenance: ProvenanceStatement
publisher: Leiden University Medical Center, the Netherlands
contact point: Kind
  fn: Jutte J.C. de Vries, Principle Investigator, Dept. LUCID, https://orcid.org/0000-0003-2530-6260
keyword: transcriptomics
keyword: Influenza
keyword: COVID-19
theme: HEAL

LLS_IOP1_partoffs_Participant_info
type: Dataset
creator: Simon Mooijaart
creator: Marian Beekman
creator: Eline Slagboom
creator: Diana van Heemst
creator: Joris Deelen
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of the offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: 10.1038/sj.ejhg.5201508; Westendorp et al 2009, doi: 10.1111/j.1532-5415.2009.02381.x). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79) as population based controls. It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. The dataset of the LLS IOP1 Partner Offspring consists of the 1671 offspring of nonagenarian siblings and their 744 partners from 421 families of whom we have physical measurements, biosamples, biomarkers, and questionnaire data. We followed this group of 2,415 middle-aged participants for their vital status till 2020, for their morbidity status till 2017.
issued: 2022-05-10T13:14:14+00:00
language: en
modified: 2022-06-13T12:03:19+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

test
type: Dataset
applicable legislation: oj
access rights: PUBLIC
creator: asdasd
description: tasdasd
issued: 2025-09-10T11:36:15.065777
language: en
modified: 2026-04-12T11:36:36.130273
provenance: ProvenanceStatement
publisher: sdasdasd
contact point: Kind
  fn: albert
keyword: adasdas
qualified relation: Relationship
  relation: dataset
  had role: example.com
theme: HEAL

PRIDE Study obstetric records
type: Dataset
creator: Marleen van Gelder
description: Selected clinical data from obstetric records covering the pregnancy period and puerperium. Necessitates additional consent, provided by ~70% of participants
issued: 2024-12-30T23:00:00+00:00
language: en
modified: 2026-04-12T11:33:41.401601
provenance: ProvenanceStatement
publisher: Radboudumc
theme: HEAL

Questionnaire data of the Personalised RISk-based MAmmascreening Study (PRISMA)
type: Dataset
applicable legislation: oj
access rights: RESTRICTED
creator: Academic Medical Center
description: The primary aim of the PRISMA study was to investigate the potential value of risk-tailored versus traditional breast cancer screening protocols in the Netherlands. Data collection took place between 2014-2019, resulting in ∼67,000 mammograms, ∼38,000 surveys, ∼10,000 blood samples and ∼600 saliva samples.
issued: 2024-07-01T11:11:11+00:00
language: en
modified: 2024-06-04T13:36:10+00:00
provenance: ProvenanceStatement
publisher: Academic Medical Center
contact point: Kind
  fn: Data Access Committee of the x UMC
keyword: example
theme: HEAL

Test Dataset
type: Dataset
creator: Me
issued: 2025-02-03T23:00:00+00:00
language: en
modified: 2026-04-12T11:36:03.886777
provenance: ProvenanceStatement
publisher: Me
contact point: Kind
  fn: Foo Bar
theme: example.com

LLS IOP2 Participant info
type: Dataset
creator: Joris Deelen
creator: Diana van Heemst
creator: Marian Beekman
creator: Eline Slagboom
creator: Simon Mooijaart
description: From the group of 2,415 LLS PartnerOffspring that participated in the LLS between 2002 and 2006, 686 participants were examined for the second time between 2006 and 2008. In total 343 offspring and their partners (as couples living together) participated, with a mean age of 63 years. Of the 286 participants of the morning program, fasted blood was collected and serum/plasma was stored. Furthermore, skin replica’s and skin biopties were taken, from which viable fibroblasts were isolated and stored. The morning group was also subjected to an oral-glucose tolerance test. Of the 400 participants of the afternoon program, non-fasted blood was collected and serum/plasma and viable PBMCs were isolated and stored. The full blood was stimulated with LPS and cytokine levels were measured. From the majority of the total participants physical measures, DXA scan and standardized photographs of the face were taken, and all participants brought first morning void of urine which was stored.
issued: 2022-07-22T15:18:08+00:00
language: en
modified: 2022-07-22T15:18:37+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

LLS IOP2 Nightingale QL16-20
type: Dataset
creator: Marian Beekman
creator: Simon Mooijaart
creator: Diana van Heemst
creator: Joris Deelen
creator: Eline Slagboom
description: From the group of 2,415 LLS PartnerOffspring that participated in the LLS between 2002 and 2006, 686 participants were examined for the second time between 2006 and 2008. In total 343 offspring and their partners (as couples living together) participated, with a mean age of 63 years. Of the 286 participants of the morning program, fasted blood was collected and serum/plasma was stored. Furthermore, skin replica’s and skin biopties were taken, from which viable fibroblasts were isolated and stored. The morning group was also subjected to an oral-glucose tolerance test. Of the 400 participants of the afternoon program, non-fasted blood was collected and serum/plasma and viable PBMCs were isolated and stored. The full blood was stimulated with LPS and cytokine levels were measured. From the majority of the total participants physical measures, DXA scan and standardized photographs of the face were taken, and all participants brought first morning void of urine which was stored.
issued: 2022-07-22T15:12:31+00:00
language: en
modified: 2022-08-09T15:05:46+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

LLS IOP2 Gripstrength
type: Dataset
creator: Joris Deelen
creator: Simon Mooijaart
creator: Eline Slagboom
creator: Diana van Heemst
creator: Marian Beekman
description: From the group of 2,415 LLS PartnerOffspring that participated in the LLS between 2002 and 2006, 686 participants were examined for the second time between 2006 and 2008. In total 343 offspring and their partners (as couples living together) participated, with a mean age of 63 years. Of the 286 participants of the morning program, fasted blood was collected and serum/plasma was stored. Furthermore, skin replica’s and skin biopties were taken, from which viable fibroblasts were isolated and stored. The morning group was also subjected to an oral-glucose tolerance test. Of the 400 participants of the afternoon program, non-fasted blood was collected and serum/plasma and viable PBMCs were isolated and stored. The full blood was stimulated with LPS and cytokine levels were measured. From the majority of the total participants physical measures, DXA scan and standardized photographs of the face were taken, and all participants brought first morning void of urine which was stored.
issued: 2022-07-22T15:16:01+00:00
language: en
modified: 2022-07-22T15:16:25+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

UroLife study quality of life questionnaire
type: Dataset
applicable legislation: oj
has code values: Q116728508
health category: Q116728508
max typical age: 80
min typical age: 18
number of records: 1451
number of unique individuals: 1451
population coverage: Patients with newly diagnosed non-muscle invasive bladder cancer aged 18-80 years from the Netherlands diagnosed between 2014-2021
retention period: PeriodOfTime
  end date: 2037-07-04
  start date: 2022-07-04
access rights: NON PUBLIC
accrual periodicity: NOT PLANNED
creator: Radboudumc
description: The EORTC QLQ-C30 and EORTC QLQ-NMIBC24 was completed at 6 weeks (n=1451) and 3 (n=1334), 15 (n=1159) and 51 months (n=588) after diagnosis.
issued: 2024-12-30T23:00:00+00:00
language: ENG
modified: 2026-04-12T11:35:09.543573
provenance: ProvenanceStatement
publisher: Radboudumc
spatial: NLD
temporal: PeriodOfTime
  end date: 2022-07-04T22:00:00+00:00
  start date: 2014-03-31T22:00:00+00:00
keyword: EORTC QLQ-C30
keyword: EORTC QLQ-NMIBC
keyword: quality of life
qualified attribution: Attribution
  agent: Alina Vrieling
  had role: principalInvestigator
qualified attribution: Attribution
  agent: World Cancer Research Fund Netherlands
  had role: funder
qualified attribution: Attribution
  agent: KWF Kankerbestrijding
  had role: funder
theme: HEAL
has legal basis: InformedConsent
has purpose: AcademicResearch

Imaging data - Nifti format
type: Distribution
description: Imaging data available in imaging format
format: NCIT C190183
issued: 2026-04-12T11:35:38.297918
language: en
license: cc-by-nc-nd3.0
modified: 2026-04-12T11:35:38.294226
rights: RightsStatement
access URL: https://www.personalizedparkinsonproject.com/home

ReLife study accelerometer data
type: Dataset
applicable legislation: oj
has code values: Q18556342
health category: Q1164529
max typical age: 75
min typical age: 18
number of records: 346
number of unique individuals: 346
population coverage: patients with localized stage I-III renal cell cancer aged 18-75 years from the Netherlands recruited from January 2018 to June 2021
retention period: PeriodOfTime
  end date: 2038-04-19
  start date: 2023-04-19
access rights: NON PUBLIC
accrual periodicity: NOT PLANNED
creator: Radboudumc
description: Accelerometer data (ActivPal) is available at 3 (n=346), 12 (n=323) and 24 months (n=271) after surgery.
issued: 2024-12-30T23:00:00+00:00
language: ENG
modified: 2026-04-12T11:33:38.094627
provenance: ProvenanceStatement
publisher: Radboudumc
spatial: NLD
temporal: PeriodOfTime
  end date: 2023-04-19T22:00:00+00:00
  start date: 2018-02-05T23:00:00+00:00
keyword: physical activity
keyword: accelerometer
keyword: ActivPal
keyword: sedentary time
qualified attribution: Attribution
  agent: World Cancer Research Fund Netherlands
  had role: funder
qualified attribution: Attribution
  agent: Alina Vrieling
  had role: principalInvestigator
qualified attribution: Attribution
  agent: KWF Kankerbestrijding
  had role: funder
theme: HEAL
has legal basis: InformedConsent
has purpose: AcademicResearch

Leiden NMR
type: Dataset
creator: Joris Deelen
creator: Diana van Heemst
creator: Eline Slagboom
creator: Simon Mooijaart
creator: Marian Beekman
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of the offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: 10.1038/sj.ejhg.5201508; Westendorp et al 2009, doi: 10.1111/j.1532-5415.2009.02381.x). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. The dataset of the LLS IOP1 Nonagenarian Siblings consists of 944 long-lived siblings from 421 families of whom we have biosamples, biomarkers, and questionnaire data. We followed these nonagenarian participants for their vital status till 2020.
issued: 2022-04-29T08:13:18+00:00
language: en
modified: 2022-06-13T12:03:33+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

Plasma endothelial markers
type: Dataset
creator: Simon Mooijaart
creator: Joris Deelen
creator: Marian Beekman
creator: Eline Slagboom
creator: Diana van Heemst
description: From the group of 343 couples (Ntotal=686_ LLS PartnerOffspring that participated in the LLS between 2006 and 2008, 500 participants were examined for the third time between 2009 and 2010. In total 250 offspring-partners couples participated, with a mean age of 66 years. Fasted blood was drawn and serum/plasma and viable PBMCs were isolated and stored. All participant were subjected to cognitive tests (ACS-90, STROOP, Picture Word Learning test, LOT, Apathy scale, CES-D), and in 367 participants 3Tesla brain MRI scans were performed and of 341 participants CT-scan of abdomen was performed.
issued: 2024-11-07T14:46:33+00:00
language: en
modified: 2024-11-07T14:47:12+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

GWAS and Allele Frequency Lookup Data Distribution for GDI MS8
type: Distribution
description: VCF file containing GWAS and allele frequency lookup data of synthetic COVID-19.cases and controls for GDI MS8 demonstration.
issued: 2026-04-12T11:33:30.779407
language: en
license: cc-zero1.0
modified: 2026-04-12T11:33:30.769468
rights: RightsStatement
access URL: https://staging-download.gdi.nbis.se/dataset/GDI-MS8-COVID19.vcf
media type: vcf

PRIDE Study questionnaire data
type: Dataset
creator: Marleen van Gelder
description: In this ongoing prospective cohort study, women complete web-based questionnaires at three time points in pregnancy (at enrollment [median gestational age 10 weeks], gestational weeks 17 and 34), 2 and 6 months after the estimated date of delivery, and, if additional consent is provided, every 6 months until the age of 7 years. Questionnaires focus on a broad range of topics, including demographic characteristics, obstetric history, maternal health, life style factors, occupational exposures, nutrition, pregnancy complications, and infant outcomes. The current analytical dataset includes >13,000 pregnancies with an estimated date of delivery in 2012-2024.
issued: 2024-12-30T23:00:00+00:00
language: en
modified: 2026-04-12T11:34:30.055726
provenance: ProvenanceStatement
publisher: Radboudumc
theme: HEAL

Test
type: Agent

EATRIS-Plus multi-omics data of a human reference cohort
type: Distribution
description: The pre-processed mult-omics data can be accessed here in the shape of a MultiAssayExperiment object (Ramos et al. 2017)
format: HDF
issued: 2026-04-12T11:34:51.894576
language: en
license: MIT
modified: 2026-04-12T11:34:51.869483
rights: RightsStatement
rights: MIT
access URL: https://doi.org/10.5281/zenodo.10782799
byte size: 108200000

Thyroid measures
type: Dataset
creator: Eline Slagboom
creator: Simon Mooijaart
creator: Diana van Heemst
creator: Marian Beekman
creator: Joris Deelen
description: From the group of 343 couples (Ntotal=686_ LLS PartnerOffspring that participated in the LLS between 2006 and 2008, 500 participants were examined for the third time between 2009 and 2010. In total 250 offspring-partners couples participated, with a mean age of 66 years. Fasted blood was drawn and serum/plasma and viable PBMCs were isolated and stored. All participant were subjected to cognitive tests (ACS-90, STROOP, Picture Word Learning test, LOT, Apathy scale, CES-D), and in 367 participants 3Tesla brain MRI scans were performed and of 341 participants CT-scan of abdomen was performed.
issued: 2024-11-07T14:49:46+00:00
language: en
modified: 2024-11-07T14:50:15+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

LLS_IOP3_OLINKcardiomatebolic_samples
type: Dataset
creator: Diana van Heemst
creator: Simon Mooijaart
creator: Joris Deelen
creator: Eline Slagboom
creator: Marian Beekman
description: From the group of 343 couples (Ntotal=686_ LLS PartnerOffspring that participated in the LLS between 2006 and 2008, 500 participants were examined for the third time between 2009 and 2010. In total 250 offspring-partners couples participated, with a mean age of 66 years. Fasted blood was drawn and serum/plasma and viable PBMCs were isolated and stored. All participant were subjected to cognitive tests (ACS-90, STROOP, Picture Word Learning test, LOT, Apathy scale, CES-D), and in 367 participants 3Tesla brain MRI scans were performed and of 341 participants CT-scan of abdomen was performed.
issued: 2024-02-09T08:29:24+00:00
language: en
modified: 2024-02-09T08:29:50+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

Overleden inwoners van Nederland naar onderliggende doodsoorzaak per kwartaal en jaar van overlijden
type: Dataset
applicable legislation: oj
max typical age: 100
min typical age: 0
access rights: PUBLIC
creator: Centraal Bureauu voor de Statistiek
description: Deze tabel bevat cijfers over de onderliggende doodsoorzaken van overleden inwoners van Nederland. De cijfers zijn uitgesplitst per kwartaal en jaar van overlijden naar een beperkt aantal doodsoorzaken. De sterfte aan COVID-19 of de ziekte veroorzaakt door het nieuwe coronavirus wordt gecodeerd met de ICD-10 codes U07.1 of U07.2. Deze codes zijn door de Wereldgezondheidsorganisatie (WHO) als 'emergency codes' of tijdelijke noodcodes neergezet en zullen later in een hoofdstuk van de ICD10 opgenomen worden. Deze codes worden daarom nu nog in de kwartaal tabel geteld bij de categorie 'Overige doodsoorzaken'. Het CBS is in het statistiekjaar 2013 overgestapt op het gebruik van internationale software voor automatisch coderen van de doodsoorzaken. Hiermee zijn de cijfers beter reproduceerbaar en internationaal vergelijkbaar. Wel zijn er enkele forse verschuivingen te zien in de doodsoorzaken (zie paragraaf 4). Gegevens beschikbaar vanaf: 1e kwartaal 1996 Status van de cijfers: De cijfers over 2024 zijn voorlopig, de overige cijfers zijn definitief. Wijzigingen per 16 mei 2025: De voorlopige cijfers over het vierde kwartaal en het totaal van 2024 zijn toegevoegd, de cijfers over de eerste drie kwartalen van 2024 zijn aangepast. Wanneer komen er nieuwe cijfers? In het derde kwartaal van 2025 verschijnen cijfers over het eerste kwartaal van 2025.
issued: 2025-05-15T22:00:00+00:00
language: nl.html
modified: 2026-04-12T11:36:59.307866
provenance: ProvenanceStatement
publisher: Centraal bureau voor de statistiek
temporal: PeriodOfTime
  end date: 2025-06-29T22:00:00+00:00
  start date: 2024-12-31T23:00:00+00:00
contact point: Kind
  fn: Centraal Bureau voor de statistiek
  has URL: https://www.cbs.nl
keyword: Doodsoorzaken
theme: HEAL

POM wearables
type: Dataset
creator: Bas Bloem
description: Wearable data of the Personalized Parkinson Project, including data obtained with a Verily watch.
issued: 2025-04-03T22:00:00+00:00
language: en
modified: 2026-04-12T11:34:16.551839
provenance: ProvenanceStatement
publisher: Radboudumc
theme: HEAL

PRIDE Study saliva samples
type: Dataset
creator: Marleen van Gelder
description: Single saliva samples for cortisol analyses collected in 2012-2020 in subgroup (N~3400). Partially analyzed, remaining samples stored at -20°C.
issued: 2024-12-30T23:00:00+00:00
language: en
modified: 2026-04-12T11:34:01.096150
provenance: ProvenanceStatement
publisher: Radboudumc
theme: HEAL

CSV-distribution of the questionnaire data of the Personalised RISk-based MAmmascreening Study (PRISMA)
type: Distribution
description: CSV file containing the questionnaire data of the PRISMA study
format: CSV
issued: 2026-04-12T11:36:48.736109
language: en
license: niet open
modified: 2026-04-12T11:36:48.727639
rights: definitely a real DPA.pdf
rights: RightsStatement
access URL: https://example.com/dataset/PRISMA/questionnaire.csv
byte size: 4096
media type: https://www.iana.org/assignments/media-types/text/csv

LLS IOP3 Partoffs Apolipoprotein platform
type: Dataset
creator: Joris Deelen
creator: Eline Slagboom
creator: Diana van Heemst
creator: Marian Beekman
creator: Simon Mooijaart
description: From the group of 343 couples (Ntotal=686_ LLS PartnerOffspring that participated in the LLS between 2006 and 2008, 500 participants were examined for the third time between 2009 and 2010. In total 250 offspring-partners couples participated, with a mean age of 66 years. Fasted blood was drawn and serum/plasma and viable PBMCs were isolated and stored. All participant were subjected to cognitive tests (ACS-90, STROOP, Picture Word Learning test, LOT, Apathy scale, CES-D), and in 367 participants 3Tesla brain MRI scans were performed and of 341 participants CT-scan of abdomen was performed.
issued: 2022-07-22T15:05:06+00:00
language: en
modified: 2022-07-22T15:05:56+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

test title
type: Dataset
applicable legislation: oj
access rights: PUBLIC
creator: hannah
description: test description
issued: 2025-09-10T11:35:34.919066
language: en
modified: 2026-04-12T11:36:31.461849
provenance: ProvenanceStatement
publisher: hannah
contact point: Kind
  fn: Test
keyword: test
qualified relation: Relationship
  relation: dataset
  had role: example.com
theme: HEAL

Dutch Parkinson Cohort (DUPARC)
type: Dataset
applicable legislation: oj
access rights: NON PUBLIC
creator: UMCG
description: Data van het DUPARC cohort, inclusief klinische data, neuroimaging (MRI en PET) en biomaterialen.
issued: 2026-04-10T11:03:48.536460
language: en
modified: 2026-04-12T11:34:32.672433
provenance: ProvenanceStatement
publisher: UMCG
contact point: Kind
  fn: DUPARC Cohort
keyword: DUPARC
keyword: Parkinson
keyword: NPC
qualified attribution: Attribution
  agent: Teus van Laar
  had role: principalInvestigator
theme: HEAL
has purpose: ResearchAndDevelopment

Personalized Parkinson Project (PPP)
type: Dataset
applicable legislation: oj
access rights: NON PUBLIC
creator: Radboudumc
description: Data van het Parkinson Op Maat cohort, inclusief klinische data, neuroimaging, biomaterialen en wearable data.
issued: 2026-04-10T11:03:40.530674
language: en
modified: 2026-04-12T11:34:27.494457
provenance: ProvenanceStatement
publisher: Radboudumc
contact point: Kind
  fn: Parkinson Op Maat Cohort
keyword: Parkinson
keyword: PPP
keyword: NPC
keyword: POM
qualified attribution: Attribution
  agent: Bas Bloem
  had role: principalInvestigator
theme: HEAL
has purpose: ResearchAndDevelopment

FU survey Voedingsvragenlijst (FFQ)
type: Dataset
creator: Eline Slagboom
creator: Diana van Heemst
creator: Joris Deelen
creator: Simon Mooijaart
creator: Marian Beekman
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of this offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: [10.1038/sj.ejhg.5201508](http://https://www.nature.com/articles/5201508); Westendorp et al 2009, doi: [10.1111/j.1532-5415.2009.02381.x](http://https://agsjournals.onlinelibrary.wiley.com/doi/10.1111/j.1532-5415.2009.02381.x)). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. Of all LLS participants HRC1.1 imputed genotypes are available.
issued: 2024-11-12T14:30:27+00:00
language: en
modified: 2024-11-12T14:30:55+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

Clinicalchemistry
type: Dataset
creator: Marian Beekman
creator: Diana van Heemst
creator: Joris Deelen
creator: Simon Mooijaart
creator: Eline Slagboom
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of the offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: 10.1038/sj.ejhg.5201508; Westendorp et al 2009, doi: 10.1111/j.1532-5415.2009.02381.x). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. The dataset of the LLS IOP1 Nonagenarian Siblings consists of 944 long-lived siblings from 421 families of whom we have biosamples, biomarkers, and questionnaire data. We followed these nonagenarian participants for their vital status till 2020.
issued: 2024-11-07T13:37:47+00:00
language: en
modified: 2024-11-07T13:38:13+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

POM imaging data
type: Dataset
creator: Bas Bloem
description: Imaging data of the Personalized Parkinson Project, including structural and functional MRI.
issued: 2025-04-03T22:00:00+00:00
language: en
modified: 2026-04-12T11:35:38.282701
provenance: ProvenanceStatement
publisher: Radboudumc
theme: HEAL

test distribu
type: Distribution
format: example.com
issued: 2026-04-12T11:36:31.481956
language: en
license: example.com
modified: 2026-04-12T11:36:31.470222
rights: RightsStatement
rights: example.com
status: COMPLETED
access URL: https://example.com/
byte size: 4000

LLS_IOP1_partoffs_LeidenNMR_Kimble
type: Dataset
creator: Diana van Heemst
creator: Joris Deelen
creator: Eline Slagboom
creator: Marian Beekman
creator: Simon Mooijaart
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of the offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: 10.1038/sj.ejhg.5201508; Westendorp et al 2009, doi: 10.1111/j.1532-5415.2009.02381.x). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79) as population based controls. It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. The dataset of the LLS IOP1 Partner Offspring consists of the 1671 offspring of nonagenarian siblings and their 744 partners from 421 families of whom we have physical measurements, biosamples, biomarkers, and questionnaire data. We followed this group of 2,415 middle-aged participants for their vital status till 2020, for their morbidity status till 2017.
issued: 2022-05-10T13:13:42+00:00
language: en
modified: 2022-06-13T12:02:47+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

LLS Questionnaire 1
type: DatasetSeries
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of this offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: [10.1038/sj.ejhg.5201508](http://https://www.nature.com/articles/5201508); Westendorp et al 2009, doi: [10.1111/j.1532-5415.2009.02381.x](http://https://agsjournals.onlinelibrary.wiley.com/doi/10.1111/j.1532-5415.2009.02381.x)). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. Of all LLS participants HRC1.1 imputed genotypes are available.
issued: 2025-10-07T20:45:33.415415
modified: 2026-04-12T11:32:55.285619
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/

COVID-19 dataset of aggregated data.
type: Dataset
creator: CSC - IT Center for Science (Finland)
description: This dataset contains aggregated data from 42193 individuals from COVID Population 12 Italy, Subgroup 2.
issued: 2024-11-08T04:00:00+00:00
language: en
modified: 2024-11-08T05:00:00+00:00
provenance: ProvenanceStatement
publisher: CSC - IT Center for Science (Finland)
contact point: Kind
  fn: Dylan Spalding
theme: HEAL

LLS IOP3 Participant info
type: Dataset
creator: Joris Deelen
creator: Diana van Heemst
creator: Eline Slagboom
creator: Marian Beekman
creator: Simon Mooijaart
description: From the group of 343 couples (Ntotal=686_ LLS PartnerOffspring that participated in the LLS between 2006 and 2008, 500 participants were examined for the third time between 2009 and 2010. In total 250 offspring-partners couples participated, with a mean age of 66 years. Fasted blood was drawn and serum/plasma and viable PBMCs were isolated and stored. All participant were subjected to cognitive tests (ACS-90, STROOP, Picture Word Learning test, LOT, Apathy scale, CES-D), and in 367 participants 3Tesla brain MRI scans were performed and of 341 participants CT-scan of abdomen was performed.
issued: 2022-07-22T15:09:50+00:00
language: en
modified: 2022-07-22T15:10:28+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

Test dataset Series
type: DatasetSeries
description: Test dataset Series
issued: 2025-09-10T11:35:59.499725
modified: 2026-04-12T11:36:05.685501
publisher: Albert Einstein
contact point: Kind
  fn: Albert Einstein

UroLife study blood samples
type: Dataset
applicable legislation: oj
has code values: Q116728508
health category: Q116728508
max typical age: 80
min typical age: 18
number of records: 1280
number of unique individuals: 1280
population coverage: Patients with newly diagnosed non-muscle invasive bladder cancer aged 18-80 years from the Netherlands diagnosed between 2014-2021
retention period: PeriodOfTime
  end date: 2037-07-04
  start date: 2022-07-04
access rights: NON PUBLIC
accrual periodicity: NOT PLANNED
creator: Radboudumc
description: EDTA and heparin plasma samples were collected at 3 (n=1280) and 15 months (n=1122) after diagnosis. Heparin plasma samples have been analysed for carotenoids at 3 and 15 months and for hsCRP at 3 months after diagnosis.
issued: 2024-12-30T23:00:00+00:00
language: ENG
modified: 2026-04-12T11:33:39.836201
provenance: ProvenanceStatement
publisher: Radboudumc
spatial: NLD
temporal: PeriodOfTime
  end date: 2022-07-04T22:00:00+00:00
  start date: 2014-03-31T22:00:00+00:00
keyword: EDTA plasma
keyword: blood
keyword: heparin plasma
qualified attribution: Attribution
  agent: World Cancer Research Fund Netherlands
  had role: funder
qualified attribution: Attribution
  agent: KWF Kankerbestrijding
  had role: funder
qualified attribution: Attribution
  agent: Alina Vrieling
  had role: principalInvestigator
theme: HEAL
has legal basis: InformedConsent
has purpose: AcademicResearch

X-omics iPSC data analysis workflow data and metadata files
type: Dataset
applicable legislation: oj
max typical age: 64
min typical age: 4
number of unique individuals: 44
access rights: NON PUBLIC
creator: Radboudumc
description: Multi-omics dataset generated from induced pluripotent stem cells (iPSC) cultures, differentiated to neurons by Ngn2 transduction, for seven days. iPSCs were derived from three different patient groups [Myotonic Dystrophy Type 1 (DM1), chromodomain-DNA-helicase-binding protein 2 (CHD2) related disorder, and N-acetyl-d-neuraminic acid synthase congenital disorders of glycosylation (NANS-CDG)]. For each disease, cell lines from three patient donors (two females and one male) along with three controls were included. Cell lines were derived from fibroblasts or peripheral blood mononuclear cells (PBMCs) through lentiviral reprogramming into iPSCs. In addition, two isogenic lines using CRISPR-Cas9 were included: a CHD2-mutant line created by editing the control line 409B, and a corrected DM1 control line generated by removing the pathogenic repeat expansion from DM1 patient line 1. Three levels of replicates were defined. For some patients, multiple independent iPSC lines were used, which are referred to as clones. Moreover, each iPSC line was differentiated into neurons in three independent experiments and cultured for seven days in vitro by the same experimenter. These differentiation replicates will be referred to as the biological replicates in this study. Lastly, for specific analyses and specific omics data sets (proteomics & metabolomics) duplicate measurements on the same sample are available as well, which will be referred to as technical replicates. The multi-omics dataset included six omics layers from 44 samples: whole exome sequencing (WES), enzymatic methylation sequencing (EMseq), RNA sequencing (RNAseq), mass spectrometry (MS)-based proteomics, and untargeted MS-based metabolomics measured at two centers namely, the Radboud university medical center (RUMC) and the Leiden University Medical Center (LUMC), MS-based targeted and untargeted lipidomics.
issued: 2026-04-10T11:03:50.752227
language: ENG
modified: 2026-04-12T11:34:35.482094
provenance: ProvenanceStatement
publisher: Radboudumc
spatial: NLD
contact point: Kind
  fn: Peter A.C. 't Hoen
  has URL: https://www.radboudumc.nl/personen/peter-bram-t-hoen
keyword: Neurons
keyword: Lipidomics
keyword: Metabolomics
keyword: Homo sapiens
keyword: Transcriptomics
keyword: Epigenomics
keyword: Proteomics
keyword: Genomics
keyword: Multi-omics
keyword: Induced pluripotent stem cells
qualified attribution: Attribution
  agent: Horizon 2020
  had role: funder
qualified attribution: Attribution
  agent: Nederlandse Wetenschaps Organisatie
  had role: funder
theme: HEAL

ReLife study quality of life questionnaire
type: Dataset
applicable legislation: oj
has code values: Q18556335
health category: Q1164529
max typical age: 75
min typical age: 18
number of records: 365
number of unique individuals: 365
population coverage: patients with localized stage I-III renal cell cancer aged 18-75 years from the Netherlands recruited from January 2018 to June 2021
retention period: PeriodOfTime
  end date: 2038-04-19
  start date: 2023-04-19
access rights: NON PUBLIC
accrual periodicity: NOT PLANNED
creator: Radboudumc
description: The EORTC QLQ-C30 was completed at 3 (n=365), 12 (n=317) and 24 months (n=279) after surgery.
issued: 2024-12-30T23:00:00+00:00
language: ENG
modified: 2026-04-12T11:35:23.647107
provenance: ProvenanceStatement
publisher: Radboudumc
spatial: NLD
temporal: PeriodOfTime
  end date: 2023-04-19T22:00:00+00:00
  start date: 2018-02-05T23:00:00+00:00
keyword: quality of life
keyword: EORTC QLQ-C30
qualified attribution: Attribution
  agent: KWF Kankerbestrijding
  had role: funder
qualified attribution: Attribution
  agent: World Cancer Research Fund Netherlands
  had role: funder
qualified attribution: Attribution
  agent: Alina Vrieling
  had role: principalInvestigator
theme: HEAL
has legal basis: InformedConsent
has purpose: AcademicResearch

test dataset aux classes
type: Dataset
applicable legislation: oj
access rights: PUBLIC
conforms to: Q19597236
creator: Albert Einstein
description: Test dataset for aux classes
issued: 2025-09-10T11:33:46.289535
language: en
modified: 2026-04-12T11:36:34.482461
provenance: ProvenanceStatement
publisher: Albert
contact point: Kind
  fn: Albert Einstein
keyword: tryout
keyword: aux classes
keyword: test
qualified attribution: Attribution
  agent: Funder1
  had role: funder
qualified relation: Relationship
  had role: last
theme: HEAL

IOP1_Partoffs
type: DatasetSeries
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of the offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: 10.1038/sj.ejhg.5201508; Westendorp et al 2009, doi: 10.1111/j.1532-5415.2009.02381.x). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79) as population based controls. It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. The dataset of the LLS IOP1 Partner Offspring consists of the 1671 offspring of nonagenarian siblings and their 744 partners from 421 families of whom we have physical measurements, biosamples, biomarkers, and questionnaire data. We followed this group of 2,415 middle-aged participants for their vital status till 2020, for their morbidity status till 2017.
issued: 2025-10-07T20:45:47.003111
modified: 2026-04-12T11:32:27.105712
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/

ProPark
type: Dataset
applicable legislation: oj
access rights: NON PUBLIC
creator: Amsterdam UMC
description: Data van het ProPark cohort, inclusief klinische data, neuroimaging, biomaterialen en wearable data.
issued: 2026-04-10T11:03:45.540770
language: en
modified: 2026-04-12T11:35:34.732427
provenance: ProvenanceStatement
publisher: Amsterdam UMC
contact point: Kind
  fn: ProPark Cohort
keyword: Parkinson
keyword: NPC
keyword: Propark
qualified attribution: Attribution
  agent: Agnita Boon
  had role: principalInvestigator
qualified attribution: Attribution
  agent: Wilma van de Berg
  had role: principalInvestigator
qualified attribution: Attribution
  agent: Dagmar Hepp
  had role: principalInvestigator
theme: HEAL
has purpose: ResearchAndDevelopment

dist
type: Distribution
description: Hello!
format: example.com
issued: 2026-04-12T11:36:16.077515
language: en
license: example.com
modified: 2026-04-12T11:36:16.062416
rights: RightsStatement
rights: example.com
status: COMPLETED
access URL: https://example.com/
byte size: 123123

PRIDE Study medication diaries
type: Dataset
creator: Marleen van Gelder
description: 6-week medication diaries covering prescription and over-the counter use, administered in the second trimester of pregnancy. Available for 1516 PRIDE Study participants (2013-2018).
issued: 2024-12-30T23:00:00+00:00
language: en
modified: 2026-04-12T11:34:41.530771
provenance: ProvenanceStatement
publisher: Radboudumc
theme: HEAL

Questionnaire data - CSV format
type: Distribution
description: Questionnaire data available in a CSV format
issued: 2026-04-12T11:35:33.046695
language: en
license: cc-by-nc-nd3.0
modified: 2026-04-12T11:35:33.043039
rights: RightsStatement
access URL: https://www.personalizedparkinsonproject.com/home
media type: https://www.iana.org/assignments/media-types/text/csv

Whole-exome sequencing of NTHL1 deficient tumors
type: Dataset
applicable legislation: oj
number of records: 17
number of unique individuals: 12
access rights: NON PUBLIC
creator: Radboudumc
description: Whole exome sequencing of 17 tumors from 12 different individuals with biallelic germline NTHL1 mutations from 9 different tissue types. Provided are 17 bam files which are mapped to human genome version GRCh37.
issued: 2026-04-10T11:03:59.967077
language: ENG
modified: 2026-04-12T11:35:07.339395
provenance: ProvenanceStatement
publisher: Radboudumc
spatial: NLD
type: STATISTICAL
contact point: Kind
  fn: Radboudumc
  has URL: https://ega-archive.org/dacs/EGAC00001001102
keyword: Whole Exome Sequencing WES
keyword: NTHL1 deficient tumor
keyword: Genome
qualified attribution: Attribution
  agent: Richarda de Voer
  had role: principalInvestigator
theme: HEAL
has legal basis: Consent
has personal data: DNACode
has purpose: NonCommercialResearch

Substudy UCC-SMART 2
type: Dataset
applicable legislation: oj
min typical age: 18
number of unique individuals: 2672
access rights: RESTRICTED
accrual periodicity: ANNUAL
creator: John Doe
description: Patients with a history of CVD or diabetes are invited to participate in the SMART-2 substudy. In this study, the baseline measurements of UCC-SMART are repeated in order to investigate the course of atherosclerosis and vascular risk factors over time, and to evaluate the effects of treatment. Patients participated in SMART-2 after a median of 9.9 years (IQR 9.2–10.8) since their inclusion in UCC-SMART. As with UCC-SMART, the findings of SMART-2 with an accompanying treatment recommendation are communicated to the patient, his or her treating medical specialist and general practitioner.
issued: 2025-09-10T11:35:21.917157
language: NLD
modified: 2026-04-12T11:36:37.689922
provenance: ProvenanceStatement
publisher: UMC Utrecht
spatial: NLD
temporal: PeriodOfTime
  start date: 2001-12-31T23:00:00+00:00
contact point: Kind
  fn: UCC SMART study group
  has URL: https://www.umcutrecht.nl/nl/landing/ucc-smart
keyword: abdominal aortic aneurysm
keyword: cerebrovascular disease
keyword: cardiovascular risk factors
keyword: risk prediction
keyword: hypertension
keyword: family history
keyword: hyperlipidemia
keyword: Cardiovascular disease
keyword: renal artery stenosis
keyword: diabetes mellitus
keyword: renal insufficiency
keyword: HIV infection
keyword: coronary artery disease
keyword: hypertensive pregnancy disorder
keyword: prospective cohort
keyword: peripheral artery disease
theme: HEAL

Continuous Vital Parameters with Clinical Data of Patients Admitted to a Dutch University Hospital
type: Dataset
creator: Bas Bredie
description: Vital parameters measured with the VisiMobile (Sotera Wireless; San Diego, CA, USA) of inpatients at Radboudumc (Nijmegen, The Netherlands). The dataset records minute-by-minute measurements of vital parameters, including heart rate, pulse rate, breathing rate, blood oxygenation, and blood pressure (systolic, diastolic, and mean arterial pressure), together with a time stamp (hour and minute). In addition to vital parameters, patient demographic data such as age, sex, and weight are included. Admission details encompass the reason for admission, medical interventions performed, diagnoses, lab orders, and prescribed medications. Furthermore, location of discharge and DNR (Do not resuscitate) status are reported. All data are available with timestamp as recorded in the EHR (electronic health record). The dataset includes approximately 20.000 admissions with an average duration of four days. The source of those admissions are about 15.000 different patients admitted between 2018 and 2024. The patients were admitted on one or more of the following departments: Surgery - Gastrointestinal Oncology, Gastroenterology and Hepatology, Acute Admission Unit, Neurology, General Internal Medicine, Urology.
issued: 2024-12-30T23:00:00+00:00
language: en
modified: 2026-04-12T11:33:52.037798
provenance: ProvenanceStatement
publisher: Radboudumc
theme: HEAL

Synthetic GoE Finnish Dataset
type: Dataset
applicable legislation: oj
health category: HealthCategoryHumanGenomic
number of records: 1
number of unique individuals: 4000
access rights: PUBLIC
conforms to: ExternallyGoverned
creator: Agent
  name: https://ror.org/04m8m1253
description: Synthetic test dataset for GoE with individuals from EE, FI, & LV
issued: 2026-04-10T11:05:51.822792
language: en
modified: 2026-04-12T11:35:52.291440
provenance: ProvenanceStatement
type: SYNTHETIC DATA
theme: HEAL

ReLife study genome-wide germline SNP data
type: Dataset
applicable legislation: oj
has code values: Q18556339
health category: Q1164529
max typical age: 75
min typical age: 18
number of records: 333
number of unique individuals: 333
population coverage: patients with localized stage I-III renal cell cancer aged 18-75 years from the Netherlands recruited from January 2018 to June 2021
retention period: PeriodOfTime
  end date: 2038-04-19
  start date: 2023-04-19
access rights: NON PUBLIC
accrual periodicity: NOT PLANNED
creator: Radboudumc
description: Isolated DNA and genome-wide germline SNP data is available for n=333 patients.
issued: 2024-12-30T23:00:00+00:00
language: ENG
modified: 2026-04-12T11:34:55.359785
provenance: ProvenanceStatement
publisher: Radboudumc
spatial: NLD
temporal: PeriodOfTime
  end date: 2023-04-19T22:00:00+00:00
  start date: 2018-02-05T23:00:00+00:00
keyword: germline SNPs
keyword: DNA
qualified attribution: Attribution
  agent: Alina Vrieling
  had role: principalInvestigator
qualified attribution: Attribution
  agent: KWF Kankerbestrijding
  had role: funder
qualified attribution: Attribution
  agent: World Cancer Research Fund Netherlands
  had role: funder
theme: HEAL
has legal basis: InformedConsent
has personal data: Genetic
has purpose: AcademicResearch

ReLife study tissue samples
type: Dataset
applicable legislation: oj
has code values: Q18556338
health category: Q1164529
max typical age: 75
min typical age: 18
population coverage: patients with localized stage I-III renal cell cancer aged 18-75 years from the Netherlands recruited from January 2018 to June 2021
retention period: PeriodOfTime
  end date: 2038-04-19
  start date: 2023-04-19
access rights: NON PUBLIC
accrual periodicity: NOT PLANNED
creator: Radboudumc
description: Permission is available for collection of tumour blocks.
issued: 2024-12-30T23:00:00+00:00
language: ENG
modified: 2026-04-12T11:35:29.719646
provenance: ProvenanceStatement
publisher: Radboudumc
spatial: NLD
temporal: PeriodOfTime
  end date: 2023-04-19T22:00:00+00:00
  start date: 2018-02-05T23:00:00+00:00
keyword: renal cell cancer FFPE samples
qualified attribution: Attribution
  agent: World Cancer Research Fund Netherlands
  had role: funder
qualified attribution: Attribution
  agent: KWF Kankerbestrijding
  had role: funder
qualified attribution: Attribution
  agent: Alina Vrieling
  had role: principalInvestigator
theme: HEAL
has legal basis: InformedConsent
has purpose: AcademicResearch

FU Castor Metingen handknijpkrachttest
type: Dataset
creator: Diana van Heemst
creator: Joris Deelen
creator: Marian Beekman
creator: Eline Slagboom
creator: Simon Mooijaart
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of this offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: [10.1038/sj.ejhg.5201508](http://https://www.nature.com/articles/5201508); Westendorp et al 2009, doi: [10.1111/j.1532-5415.2009.02381.x](http://https://agsjournals.onlinelibrary.wiley.com/doi/10.1111/j.1532-5415.2009.02381.x)). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. Of all LLS participants HRC1.1 imputed genotypes are available.
issued: 2024-11-12T13:27:39+00:00
language: en
modified: 2024-11-12T13:37:41+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

Test Distribution
type: Distribution
description: THis is a test distribution
format: plain
issued: 2026-04-12T11:36:03.898359
language: en
license: cc-by-nc-nd3.0
modified: 2026-04-12T11:36:03.894375
rights: RightsStatement
access URL: http://example.com/

UroLife study molecular subtypes
type: Dataset
applicable legislation: oj
has code values: Q116728508
health category: Q116728508
max typical age: 80
min typical age: 18
number of records: 389
number of unique individuals: 389
population coverage: Patients with newly diagnosed non-muscle invasive bladder cancer aged 18-80 years from the Netherlands diagnosed between 2014-2021
retention period: PeriodOfTime
  end date: 2037-07-04
  start date: 2022-07-04
access rights: NON PUBLIC
accrual periodicity: NOT PLANNED
creator: Radboudumc
description: Molecular subtype based on immunohistrochemistry performed on tissue microarrays is available for 389 T1 NMIBC tumours.
issued: 2024-12-30T23:00:00+00:00
language: ENG
modified: 2026-04-12T11:35:26.752213
provenance: ProvenanceStatement
publisher: Radboudumc
spatial: NLD
temporal: PeriodOfTime
  end date: 2022-07-04T22:00:00+00:00
  start date: 2014-03-31T22:00:00+00:00
keyword: molecular subtypes
qualified attribution: Attribution
  agent: Alina Vrieling
  had role: principalInvestigator
qualified attribution: Attribution
  agent: World Cancer Research Fund Netherlands
  had role: funder
qualified attribution: Attribution
  agent: KWF Kankerbestrijding
  had role: funder
theme: HEAL
has legal basis: InformedConsent
has purpose: AcademicResearch

ReLife study body composition data
type: Dataset
applicable legislation: oj
has code values: Q18556341
health category: Q1164529
max typical age: 75
min typical age: 18
number of records: 349
number of unique individuals: 349
population coverage: patients with localized stage I-III renal cell cancer aged 18-75 years from the Netherlands recruited from January 2018 to June 2021
retention period: PeriodOfTime
  end date: 2038-04-19
  start date: 2023-04-19
access rights: NON PUBLIC
accrual periodicity: NOT PLANNED
creator: Radboudumc
description: CT-based assessment of body composition is available for n=349 patients.
issued: 2024-12-30T23:00:00+00:00
language: ENG
modified: 2026-04-12T11:34:11.445511
provenance: ProvenanceStatement
publisher: Radboudumc
spatial: NLD
temporal: PeriodOfTime
  end date: 2023-04-19T22:00:00+00:00
  start date: 2018-02-05T23:00:00+00:00
keyword: subcutaneous adipose tissue
keyword: skeletal muscle
keyword: visceral adipose tissue
keyword: body composition
keyword: skeletal muscle radiodensity
qualified attribution: Attribution
  agent: World Cancer Research Fund Netherlands
  had role: funder
qualified attribution: Attribution
  agent: Alina Vrieling
  had role: principalInvestigator
qualified attribution: Attribution
  agent: KWF Kankerbestrijding
  had role: funder
theme: HEAL
has legal basis: InformedConsent
has purpose: AcademicResearch

UroLife study genome-wide germline SNP data
type: Dataset
applicable legislation: oj
has code values: Q116728508
health category: Q116728508
max typical age: 80
min typical age: 18
number of records: 1213
number of unique individuals: 1213
population coverage: Patients with newly diagnosed non-muscle invasive bladder cancer aged 18-80 years from the Netherlands diagnosed between 2014-2021
retention period: PeriodOfTime
  end date: 2037-07-04
  start date: 2022-07-04
access rights: NON PUBLIC
accrual periodicity: NOT PLANNED
creator: Radboudumc
description: Isolated DNA and genome-wide germline SNP data is available for 1213 patients.
issued: 2024-12-30T23:00:00+00:00
language: ENG
modified: 2026-04-12T11:33:50.053281
provenance: ProvenanceStatement
publisher: Radboudumc
spatial: NLD
temporal: PeriodOfTime
  end date: 2022-07-04T22:00:00+00:00
  start date: 2014-03-31T22:00:00+00:00
keyword: DNA
keyword: germline SNPs
qualified attribution: Attribution
  agent: Alina Vrieling
  had role: principalInvestigator
qualified attribution: Attribution
  agent: World Cancer Research Fund Netherlands
  had role: funder
qualified attribution: Attribution
  agent: KWF Kankerbestrijding
  had role: funder
theme: HEAL
has legal basis: InformedConsent
has personal data: Genetic
has purpose: AcademicResearch

FU survey Fysieke activeit (SQUASH) OUD
type: Dataset
creator: Simon Mooijaart
creator: Diana van Heemst
creator: Eline Slagboom
creator: Marian Beekman
creator: Joris Deelen
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of this offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: [10.1038/sj.ejhg.5201508](http://https://www.nature.com/articles/5201508); Westendorp et al 2009, doi: [10.1111/j.1532-5415.2009.02381.x](http://https://agsjournals.onlinelibrary.wiley.com/doi/10.1111/j.1532-5415.2009.02381.x)). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. Of all LLS participants HRC1.1 imputed genotypes are available.
issued: 2024-11-12T10:43:54+00:00
language: en
modified: 2024-11-12T10:44:55+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

Cellcounts
type: Dataset
creator: Diana van Heemst
creator: Marian Beekman
creator: Eline Slagboom
creator: Joris Deelen
creator: Simon Mooijaart
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of the offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: 10.1038/sj.ejhg.5201508; Westendorp et al 2009, doi: 10.1111/j.1532-5415.2009.02381.x). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79) as population based controls. It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. The dataset of the LLS IOP1 Partner Offspring consists of the 1671 offspring of nonagenarian siblings and their 744 partners from 421 families of whom we have physical measurements, biosamples, biomarkers, and questionnaire data. We followed this group of 2,415 middle-aged participants for their vital status till 2020, for their morbidity status till 2017.
issued: 2022-05-10T12:29:13+00:00
language: en
modified: 2022-06-13T12:02:08+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

PRIDE Study blood samples
type: Dataset
creator: Marleen van Gelder
description: First trimester blood samples (plasma, serum, whole blood) of ~1000 PRIDE Study participants, available for genetic and biochemical analyses. Stored at -80°C.
issued: 2024-12-30T23:00:00+00:00
language: en
modified: 2026-04-12T11:35:00.697052
provenance: ProvenanceStatement
publisher: Radboudumc
theme: HEAL

PRIDE Study nutrition
type: Dataset
creator: Marleen van Gelder
description: Food frequency questionnaire administered in early pregnancy, assessing multiple macronutrients and micronutrients.
issued: 2024-12-30T23:00:00+00:00
language: en
modified: 2026-04-12T11:35:24.962252
provenance: ProvenanceStatement
publisher: Radboudumc
theme: HEAL

ReLife study food frequency questionnaire
type: Dataset
applicable legislation: oj
has code values: Q18556334
health category: Q1164529
max typical age: 75
min typical age: 18
number of records: 352
number of unique individuals: 352
population coverage: patients with localized stage I-III renal cell cancer aged 18-75 years from the Netherlands recruited from January 2018 to June 2021
retention period: PeriodOfTime
  end date: 2038-04-19
  start date: 2023-04-19
access rights: NON PUBLIC
accrual periodicity: NOT PLANNED
creator: Radboudumc
description: A 163-item Food Frequency questionnaire was completed at 3 (n=352), 12 (n=330) and 24 months (n=275) after surgery.
issued: 2024-12-30T23:00:00+00:00
language: ENG
modified: 2026-04-12T11:35:14.491936
provenance: ProvenanceStatement
publisher: Radboudumc
spatial: NLD
temporal: PeriodOfTime
  end date: 2023-04-19T22:00:00+00:00
  start date: 2018-02-05T23:00:00+00:00
keyword: food items
keyword: food frequencey questionnaire
keyword: micronutrients
keyword: macronutrients
qualified attribution: Attribution
  agent: KWF Kankerbestrijding
  had role: funder
qualified attribution: Attribution
  agent: Alina Vrieling
  had role: principalInvestigator
qualified attribution: Attribution
  agent: World Cancer Research Fund Netherlands
  had role: funder
theme: HEAL
has legal basis: InformedConsent
has purpose: AcademicResearch

AMARA dataset 1
type: Dataset
applicable legislation: oj
access rights: RESTRICTED
creator: Radboudumc
description: Collection of CT scan data of the thorax from one academic medical center in the Netherlands, including metadata on lung cancer status, men and women aged 18 and above.
is referenced by: s00330-025-11829-1
issued: 2026-04-10T11:03:34.492709
language: ENG
modified: 2026-04-12T11:35:16.606639
provenance: ProvenanceStatement
publisher: Radboudumc
contact point: Kind
  fn: Colin Jacobs
keyword: thorax CT imaging
keyword: CT lung
keyword: lung cancer
qualified attribution: Attribution
  agent: KWF Kankerbestrijding
  had role: funder
qualified attribution: Attribution
  agent: Colin Jacobs
theme: HEAL

LLS IOP2 Clinical chemistry
type: Dataset
creator: Eline Slagboom
creator: Marian Beekman
creator: Simon Mooijaart
creator: Joris Deelen
creator: Diana van Heemst
description: From the group of 2,415 LLS PartnerOffspring that participated in the LLS between 2002 and 2006, 686 participants were examined for the second time between 2006 and 2008. In total 343 offspring and their partners (as couples living together) participated, with a mean age of 63 years. Of the 286 participants of the morning program, fasted blood was collected and serum/plasma was stored. Furthermore, skin replica’s and skin biopties were taken, from which viable fibroblasts were isolated and stored. The morning group was also subjected to an oral-glucose tolerance test. Of the 400 participants of the afternoon program, non-fasted blood was collected and serum/plasma and viable PBMCs were isolated and stored. The full blood was stimulated with LPS and cytokine levels were measured. From the majority of the total participants physical measures, DXA scan and standardized photographs of the face were taken, and all participants brought first morning void of urine which was stored.
issued: 2022-07-22T15:14:19+00:00
language: en
modified: 2022-07-22T15:15:05+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

testtest
type: Dataset
applicable legislation: oj
access rights: PUBLIC
creator: alb
description: another test
issued: 2025-09-10T11:34:00.526942
language: en
modified: 2026-04-12T11:36:57.262863
provenance: ProvenanceStatement
publisher: albi
contact point: Kind
  fn: al
keyword: test 2
theme: HEAL

test
type: Distribution
format: example.com
issued: 2026-04-12T11:36:26.720644
language: en
license: example.com
modified: 2026-04-12T11:36:26.710788
rights: RightsStatement
rights: example.com
access URL: https://example.com/
byte size: 1234

FU survey Alg vragenlijst LLS
type: Dataset
creator: Marian Beekman
creator: Joris Deelen
creator: Diana van Heemst
creator: Eline Slagboom
creator: Simon Mooijaart
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of this offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: [10.1038/sj.ejhg.5201508](http://https://www.nature.com/articles/5201508); Westendorp et al 2009, doi: [10.1111/j.1532-5415.2009.02381.x](http://https://agsjournals.onlinelibrary.wiley.com/doi/10.1111/j.1532-5415.2009.02381.x)). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. Of all LLS participants HRC1.1 imputed genotypes are available.
issued: 2024-11-12T10:51:13+00:00
language: en
modified: 2024-11-12T10:52:52+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

UroLife study food frequency questionnaire
type: Dataset
applicable legislation: oj
has code values: Q116728508
health category: Q116728508
max typical age: 80
min typical age: 18
number of records: 1439
number of unique individuals: 1439
population coverage: Patients with newly diagnosed non-muscle invasive bladder cancer aged 18-80 years from the Netherlands diagnosed between 2014-2021
retention period: PeriodOfTime
  end date: 2037-07-04
  start date: 2022-07-04
access rights: NON PUBLIC
accrual periodicity: NOT PLANNED
creator: Radboudumc
description: A 163-item Food Frequency questionnaire was completed at 6 weeks (referring to pre-diagnosis lifestyle; n=1439)) and 3 (n=1316), 15 (n=1143) en 51 months (n<589) after diagnosis.
issued: 2024-12-30T23:00:00+00:00
language: ENG
modified: 2026-04-12T11:34:43.841413
provenance: ProvenanceStatement
publisher: Radboudumc
spatial: NLD
temporal: PeriodOfTime
  end date: 2022-07-04T22:00:00+00:00
  start date: 2014-03-31T22:00:00+00:00
keyword: food items
keyword: food frequencey questionnaire
keyword: micronutrients
keyword: macronutrients
qualified attribution: Attribution
  agent: Alina Vrieling
  had role: principalInvestigator
qualified attribution: Attribution
  agent: KWF Kankerbestrijding
  had role: funder
qualified attribution: Attribution
  agent: World Cancer Research Fund Netherlands
  had role: funder
theme: HEAL
has legal basis: InformedConsent
has purpose: AcademicResearch

Exploratory Test DatasetSeries
type: DatasetSeries
description: Test
issued: 2026-04-11T11:19:41.977775
modified: 2026-04-12T11:36:54.760401
contact point: Kind
  fn: Test

Exploratory Test Dataset
type: Dataset
applicable legislation: oj
has code values: values
has coding system: system
health category: health
max typical age: 123
min typical age: 20
number of records: 123
number of unique individuals: 456
population coverage: http://example.com/population/coverage
access rights: PUBLIC
accrual periodicity: daily
creator: Test Creator
  type: Agent
  type: type
description: This is a test description for exploratory testing.
is referenced by: http://example.com/publication/123
issued: 2026-04-11T11:19:37.995678
language: en
modified: 2026-03-12T15:23:00+00:00
provenance: ProvenanceStatement
publisher: Test Publisher
  type: Agent
  type: type
spatial: nl
identifier: Identifier
  notation: nfc33cbbdaaee479391ce9dc4d746d199b7
contact point: Kind
  fn: Test Contact
  has URL: http://example.com/
keyword: test
qualified attribution: Attribution
  agent: Test Agent
theme: HEAL
has legal basis: Consent
has personal data: Gender
has purpose: ScientificResearch

LLS_IOP3_OLINKcardiomatebolic_metadata
type: Dataset
creator: Simon Mooijaart
creator: Joris Deelen
creator: Diana van Heemst
creator: Eline Slagboom
creator: Marian Beekman
description: From the group of 343 couples (Ntotal=686_ LLS PartnerOffspring that participated in the LLS between 2006 and 2008, 500 participants were examined for the third time between 2009 and 2010. In total 250 offspring-partners couples participated, with a mean age of 66 years. Fasted blood was drawn and serum/plasma and viable PBMCs were isolated and stored. All participant were subjected to cognitive tests (ACS-90, STROOP, Picture Word Learning test, LOT, Apathy scale, CES-D), and in 367 participants 3Tesla brain MRI scans were performed and of 341 participants CT-scan of abdomen was performed.
issued: 2024-02-09T08:28:35+00:00
language: en
modified: 2024-02-09T08:29:02+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

Nederlands RBD Cohort
type: Dataset
applicable legislation: oj
access rights: NON PUBLIC
creator: Amsterdam UMC
description: Data van het Nederlands RBD cohort, inclusief klinische data, neuroimaging, biomaterialen en wearable data.
issued: 2026-04-10T11:03:26.333380
language: en
modified: 2026-04-12T11:34:46.092194
provenance: ProvenanceStatement
publisher: Amsterdam UMC
contact point: Kind
  fn: Nederlands RBD Cohort
keyword: NPC
keyword: RBD
qualified attribution: Attribution
  agent: Ysbrand van der Werf
  had role: principalInvestigator
theme: HEAL
has purpose: ResearchAndDevelopment

ReLife study clinical data
type: Dataset
applicable legislation: oj
has code values: Q18556336
health category: Q1164529
max typical age: 75
min typical age: 18
number of records: 368
number of unique individuals: 368
population coverage: patients with localized stage I-III renal cell cancer aged 18-75 years from the Netherlands recruited from January 2018 to June 2021
retention period: PeriodOfTime
  end date: 2038-04-19
  start date: 2023-04-19
access rights: NON PUBLIC
accrual periodicity: NOT PLANNED
creator: Radboudumc
description: Data on tumour characteristics, treatment, complications, recurrence(s), progression and mortality were collected from medical records by data managers of the Netherlands Cancer Registry (N=368).
issued: 2024-12-30T23:00:00+00:00
language: ENG
modified: 2026-04-12T11:34:04.085435
provenance: ProvenanceStatement
publisher: Radboudumc
spatial: NLD
temporal: PeriodOfTime
  end date: 2023-04-19T22:00:00+00:00
  start date: 2018-02-05T23:00:00+00:00
keyword: mortality
keyword: complications
keyword: recurrence
keyword: progression
keyword: clinical data
keyword: treatment
qualified attribution: Attribution
  agent: Alina Vrieling
  had role: principalInvestigator
qualified attribution: Attribution
  agent: World Cancer Research Fund Netherlands
  had role: funder
qualified attribution: Attribution
  agent: KWF Kankerbestrijding
  had role: funder
theme: HEAL
has legal basis: InformedConsent
has purpose: AcademicResearch

test series
type: DatasetSeries
description: test series
issued: 2025-09-10T11:36:05.832450
modified: 2026-04-12T11:36:18.094275
publisher: Alb
contact point: Kind
  fn: Albert

example dataset
type: Dataset
applicable legislation: oj
access rights: PUBLIC
creator: maastricht
description: Description of a dataset
issued: 2025-09-10T11:35:01.608355
language: en
modified: 2026-04-12T11:37:11.128299
provenance: ProvenanceStatement
publisher: Maastricht
contact point: Kind
  fn: Patrick Dekker
keyword: onboarding
keyword: http mondo.org 12344
keyword: FIV
theme: HEAL

mailto:…
type: Kind
fn: Alina Vrieling
has URL: https://www.radboudumc.nl/personen/alina-vrieling

Data access request to the Whole-exome sequencing of NTHL1 deficient tumors
type: Distribution
description: This distribution points to a link that contains17 bam files corresponding to the whole-exome sequencing of NTHL1 deficient tumors
issued: 2026-04-12T11:35:07.362962
language: ENG
license: niet-open
modified: 2026-04-12T11:35:07.350175
rights: EGAD00001004534
rights: RightsStatement
access URL: https://ega-archive.org/datasets/EGAD00001004534
byte size: 319500000000
media type: htts://publications.europa.eu/resource/authority/file-type/BIN

Distribution 1
type: Distribution
format: HDF
issued: 2026-04-12T11:34:35.524611
language: en
license: MIT
modified: 2026-04-12T11:34:35.491512
rights: MIT
rights: RightsStatement
access URL: https://doi.org/10.5281/zenodo.19133725
byte size: 13387500

https://ckan-test.healthdata.nl/catalog.jsonld
type: PagedCollection
items per page: 100
last: https://ckan-test.healthdata.nl/catalog.jsonld
last page: https://ckan-test.healthdata.nl/catalog.jsonld
next: https://ckan-test.healthdata.nl/catalog.jsonld
next page: https://ckan-test.healthdata.nl/catalog.jsonld
total items: 181

UroLife study clinical data
type: Dataset
applicable legislation: oj
has code values: Q116728508
health category: Q116728508
max typical age: 80
min typical age: 18
number of records: 1512
number of unique individuals: 1512
population coverage: Patients with newly diagnosed non-muscle invasive bladder cancer aged 18-80 years from the Netherlands diagnosed between 2014-2021
retention period: PeriodOfTime
  end date: 2037-07-04
  start date: 2022-07-04
access rights: NON PUBLIC
accrual periodicity: NOT PLANNED
creator: Radboudumc
description: Data on tumour characteristics, treatment, and recurrence(s), progression and mortality were collected from medical records by data managers of the Netherlands Cancer Registry (N=1512).
issued: 2024-12-30T23:00:00+00:00
language: ENG
modified: 2026-04-12T11:34:57.717587
provenance: ProvenanceStatement
publisher: Radboudumc
spatial: NLD
temporal: PeriodOfTime
  end date: 2022-07-04T22:00:00+00:00
  start date: 2014-03-31T22:00:00+00:00
keyword: progression
keyword: recurrence
keyword: clinical data
keyword: treatment
keyword: mortality
qualified attribution: Attribution
  agent: Alina Vrieling
  had role: principalInvestigator
qualified attribution: Attribution
  agent: KWF Kankerbestrijding
  had role: funder
qualified attribution: Attribution
  agent: World Cancer Research Fund Netherlands
  had role: funder
theme: HEAL
has legal basis: InformedConsent
has purpose: AcademicResearch

CSV-distribution of the questionnaire data of the Personalised RISk-based MAmmascreening Study (PRISMA)
type: Distribution
description: CSV file containing the questionnaire data of the PRISMA study
format: CSV
issued: 2026-04-12T11:36:46.976567
language: en
license: niet open
modified: 2026-04-12T11:36:46.970071
rights: definitely a real DPA.pdf
rights: RightsStatement
access URL: https://example.com/dataset/PRISMA/questionnaire.csv
byte size: 4096
media type: https://www.iana.org/assignments/media-types/text/csv

CSV-distribution of the questionnaire data of the Personalised RISk-based MAmmascreening Study (PRISMA)
type: Distribution
description: CSV file containing the questionnaire data of the PRISMA study
format: CSV
issued: 2026-04-12T11:36:45.257750
language: en
license: niet open
modified: 2026-04-12T11:36:45.246024
rights: RightsStatement
rights: definitely a real DPA.pdf
access URL: https://example.com/dataset/PRISMA/questionnaire.csv
byte size: 4096
media type: https://www.iana.org/assignments/media-types/text/csv

Tumor mutational landscape in individuals with CMMRD
type: Dataset
applicable legislation: oj
number of records: 16
number of unique individuals: 16
access rights: NON PUBLIC
creator: Radboudumc
description: Whole exome sequencing data from the tumors (n=16) of individuals with constitutional mismatch repair deficiency. Data was aligned to GRCh38.
is referenced by: s41467-025-59775-2
issued: 2026-04-10T11:03:56.662845
language: ENG
modified: 2026-04-12T11:35:04.021376
provenance: ProvenanceStatement
publisher: Radboudumc
spatial: NLD
type: STATISTICAL
contact point: Kind
  fn: Radboud University Medical Center
  has URL: https://ega-archive.org/dacs/EGAC00001001102
keyword: CMMRD tumors
keyword: WES
qualified attribution: Attribution
  agent: Richarda de Voer
  had role: principalInvestigator
theme: HEAL
has legal basis: Consent
has personal data: DNACode
has purpose: NonCommercialResearch

FU survey Gevoel en gedrag (CES-D)
type: Dataset
creator: Diana van Heemst
creator: Joris Deelen
creator: Eline Slagboom
creator: Simon Mooijaart
creator: Marian Beekman
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of this offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: [10.1038/sj.ejhg.5201508](http://https://www.nature.com/articles/5201508); Westendorp et al 2009, doi: [10.1111/j.1532-5415.2009.02381.x](http://https://agsjournals.onlinelibrary.wiley.com/doi/10.1111/j.1532-5415.2009.02381.x)). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. Of all LLS participants HRC1.1 imputed genotypes are available.
issued: 2024-11-12T14:19:43+00:00
language: en
modified: 2024-11-12T14:20:15+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

peter-bram.thoen@radboudumc.nl
type: Kind
fn: Peter A.C. 't Hoen
has URL: https://www.radboudumc.nl/personen/peter-bram-t-hoen

Q1 FFQ Food group key
type: Dataset
creator: Diana van Heemst
creator: Eline Slagboom
creator: Simon Mooijaart
creator: Joris Deelen
creator: Marian Beekman
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of this offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: [10.1038/sj.ejhg.5201508](http://https://www.nature.com/articles/5201508); Westendorp et al 2009, doi: [10.1111/j.1532-5415.2009.02381.x](http://https://agsjournals.onlinelibrary.wiley.com/doi/10.1111/j.1532-5415.2009.02381.x)). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. Of all LLS participants HRC1.1 imputed genotypes are available.
issued: 2024-11-12T14:53:44+00:00
language: en
modified: 2024-11-12T14:54:30+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

test 2
type: Distribution
format: example.com
issued: 2026-04-12T11:36:29.909237
language: en
license: example.com
modified: 2026-04-12T11:36:29.903415
rights: example.com
rights: RightsStatement
access URL: https://example.com/
byte size: 12312

FU Castor Medicatiegebruik
type: Dataset
creator: Eline Slagboom
creator: Marian Beekman
creator: Diana van Heemst
creator: Simon Mooijaart
creator: Joris Deelen
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of this offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: [10.1038/sj.ejhg.5201508](http://https://www.nature.com/articles/5201508); Westendorp et al 2009, doi: [10.1111/j.1532-5415.2009.02381.x](http://https://agsjournals.onlinelibrary.wiley.com/doi/10.1111/j.1532-5415.2009.02381.x)). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. Of all LLS participants HRC1.1 imputed genotypes are available.
issued: 2024-11-12T14:28:12+00:00
language: en
modified: 2024-11-12T14:28:31+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL

FU Castor Thuis biomateriaal
type: Dataset
creator: Eline Slagboom
creator: Diana van Heemst
creator: Marian Beekman
creator: Joris Deelen
creator: Simon Mooijaart
description: For the Leiden Longevity Study, long-lived siblings of European descent were recruited together with their offspring and the partners of this offspring between 2002 and 2006. Families were recruited if at least two long-lived siblings were alive and fulfilled the age criterion of 89 years or older for males and 91 years or older for females, representing less than 0.5% of the Dutch population in 2001 (Schoenmaker et al 2006, doi: [10.1038/sj.ejhg.5201508](http://https://www.nature.com/articles/5201508); Westendorp et al 2009, doi: [10.1111/j.1532-5415.2009.02381.x](http://https://agsjournals.onlinelibrary.wiley.com/doi/10.1111/j.1532-5415.2009.02381.x)). In total 944 long-lived siblings were included with a mean age of 94 years (range 89-104), 1671 offspring (61 years, 34-81) and 744 partners (60 years, 30-79). It is family based study consists of 1671 offspring of 421 nonagenarians sibling pairs of Dutch descent, and their 744 partners. Of all LLS participants HRC1.1 imputed genotypes are available.
issued: 2024-11-12T14:45:40+00:00
language: en
modified: 2024-11-12T14:46:05+00:00
provenance: ProvenanceStatement
publisher: Leiden University Medical Center
contact point: Kind
  fn: Contact Adress LLS
  has URL: https://leidenlangleven.nl/data-access/
theme: HEAL